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OctoberDecember 2025: troriluzole Biohaven is awaiting the FDA decision for troriluzole for the treatment of spinocerebellar ataxia (SCA), a rare progressive neurodegenerative disorder characterized by poor balance and muscle coordination

One RCT demonstrated improved cardiometabolic risk markers in older adults losing 8% body weight from baseline with energy-restriction and exercise (vs

Furthermore, in a 12-week trial, semaglutide was shown to reduce body weight predominantly through appetite suppression, but this effect was also accompanied by a marked reduction in preference for high-fat foods (Friedrichsen et al., 2021)

While safety data from this trial is encouraging, the sample size is too small for any meaningful conclusions to be drawn

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Alternative Therapies, Diet, HRT, Managing Weight At ENDO 2025 in San Francisco, an important study was presented exploring the effect of hormone replacement therapy (HRT) on weight loss in postmenopausal women taking tirzepatide (Mounjaro), a medication licensed for the management of type 2 diabetes and obesity